Atherosclerosis Susceptibility in Mice Is Independent of ...

2015-11-12 · 2012; 209:775–792. doi: 10.1084/jem.20112422. Crossref Medline Google Scholar; 31. Palinski W, Hörkkö S, Miller E, Steinbrecher UP, Powell HC, Curtiss LK, Witztum JL. Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice.

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Krónikus limfocitás leukémia – Wikipédia

2021-8-8 · A krónikus limfoid leukémia (CLL: chronic lymphocytic leukemia) vagy más néven B-sejtes krónikus limfocitás leukémia (B-CLL) egy limfoproliferatív betegség, a leggyakrabban előforduló felnőttkori leukémia típus,[2][3] mely a B-limfociták daganatos felszaporodásával jár. CLL-ben egyetlen B …

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Mosnier, Laurent

Bouma, B. N., Mosnier, L. O., Meijers, J. C. M., Griffin, J. H. Factor XI dependent and independent activation of thrombin activatable fibrinolysis inhibitor (TAFI ...

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Aggregation Susceptibility of Low-Density Lipoproteins—A ...

2021-4-19 · 1. Introduction. Strong evidence from epidemiologic, genetic, and clinical studies has shown that low-density lipoprotein (LDL) particles are causal agents in atherogenesis, the process causing atherosclerotic cardiovascular disease (ASCVD) [].During atherogenesis, circulating LDL particles enter the subendothelial extracellular space of the arterial wall.

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Liste türkischer Vornamen – Wikipedia

2021-8-26 · Es gibt verschiedene Arten von Kosenamen im Türkischen. So werden einige wenige türkische Namen, wie es auch bei einigen deutschen Vornamen der Fall ist, manchmal im Alltag abgekürzt. Beispiele sind Musti (von Mustafa), Yase (von Yasemin), Kübi (von Kübra) oder Mel (von Melisa oder Melis).

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Team:Marburg/Description

2019-12-19 · Genome sequencing has proven that our strain is 99.8% identical to the much better studied strain Synechococcus elongatus PCC 7942, which is surprising since both strains were isolated from completely different locations. While UTEX 2973 tolerates high …

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The Role of the Endothelium in Premature Atherosclerosis ...

2021-4-5 · Atherosclerosis is a complex progressive and systematic artery disease that involves the intima of the large and middle artery vessels. The inflammation has a key role in the pathophysiological process of the disease and the infiltration of the intima from monocytes, macrophages and T-lymphocytes combined with endothelial dysfunction and ...

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Malondialdehyde Epitopes as Targets of Immunity and the ...

2016-1-1 · 3.1. MDA Modification of Amino Acids and Proteins. MDA-modified biomolecules such as free amino acids or proteins have been identified in different tissues and body fluids in humans and animals in vivo (Akalin et al., 2007, Gonenc et al., 2001, Imai et al., 2008, Pamplona et al., 2005, Weismann et al., 2011) deed, at neutral pH in the presence of free lysine (Lys) and arginine (Arg), MDA can ...

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Host–Guest Interaction Driven Peptide Assembly into ...

2021-7-1 · Cryogenic TEM (Cryo-TEM) was performed on a JEOL-JEM 2100 TEM instrument (approximately 90 K, 120 kV) equipped with a SC 1000 charge-coupled device (CCD) camera (Gatan, Inc., USA). A liquid droplet of P1/tri-β-CD (3 μL) was transferred to an ultrathin …

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The TLR and IL-1 signalling network at a glance | Journal ...

The interaction of components of bacterial and viral pathogens with Toll-like receptors (TLRs), or the activation of the receptors for interleukin 1 (IL-1), IL-18 or IL-33. leads to the recruitment of the adaptor molecules myeloid differentiation primary response gene 88 (MyD88) and/or Toll-interleukin receptor domain containing adaptor-inducing interferon-β (TRIF, also known as TICAM1), and ...

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Some Misconceptions about Understanding Autoimmunity ...

1997-6-16 · There is abundant evidence that TNF-α and LT-α are critical in the development of EAE, and in the human disease, MS (3–12).Both TNF-α and LT-α mRNA and protein are in the central nervous system in acute EAE (3–6).T cell clones, reactive to myelin basic protein, are more capable of mediating EAE, when they produce higher amounts of TNF-α and LT-α ().

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IL-22 is related to development of human colon cancer by ...

2013-2-5 · It has been previously reported that IL-22, one of the cytokines secreted by Th17 cells, demonstrates both a protective and inflammatory promotion effect in inflammatory bowel disease (IBD) through STAT3 signaling activation. We sought to investigate the role of IL-22 expression in colon cancer (CC). The expression of IL-22 and related molecules were detected in human CC, the detail function ...

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Enterocyte-specific A20 deficiency sensitizes to tumor ...

2010-6-7 · It was previously reported that defective NF-κB activity in intestinal epithelium as a result of enterocyte-specific ablation of the regulatory subunit of the IKK complex NEMO, as well as of enterocyte-specific RelA deficiency, causes spontaneous colitis (Nenci et al., 2007; Steinbrecher et al., 2008). It can be hypothesized that this ...

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Liquid-Liquid Phase Separation of Tau Driven by ...

2021-1-22 · Amyloid aggregation of tau protein is implicated in neurodegenerative diseases, yet its facilitating factors are poorly understood. Recently, tau has been shown to undergo liquid liquid phase separation (LLPS) both in vivo and in vitro.LLPS was shown to facilitate tau amyloid aggregation in certain cases, while being independent of aggregation in other cases.

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Constitutive STAT5 activation regulates Paneth and Paneth ...

2019-4-4 · Clostridium difficile impairs Paneth cells, driving intestinal inflammation that exaggerates colitis. Besides secreting bactericidal products to restrain C. difficile, Paneth cells act as guardians that constitute a niche for intestinal epithelial stem cell (IESC) …

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TAK1: a potent tumour necrosis factor inhibitor for the ...

2020-9-2 · 2. TAK1. Transforming growth factor-β-activated kinase 1 (TAK1) serves as a key node in the TNF inflammatory signalling pathway. It is a serine/threonine kinase and can be activated by a range of proinflammatory cytokines and ligands including TNF, interleukin-1β …

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Complementary Roles for Scavenger Receptor A and CD36 of ...

1998-12-21 · Monocytes and macrophages secrete reactive oxygen species when they adhere via MSR-A to surfaces bearing fibrillar β-amyloid, a ligand for these receptors ().H 2 O 2 secreted by these cells could oxidize LDL trapped in the subendothelium, and both oxLDL …

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(PDF) ATP6V0d2 controls Leishmania parasitophorous …

2019-6-14 · Parasite-mediated expression of macrophage scavenger receptor CD36 is associated with ox-LDL-mediated PV volume recovery in ATP6V 0 d2-KD. A. LDL-R, …

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Monocyte Fate in Atherosclerosis | Arteriosclerosis ...

2014-12-23 · Monocytes Are Protagonists of Atherosclerosis. Renewed interest in monocyte biology began with the subdivision of monocytes into 2 main subsets. 4 In mice, monocytes can be distinguished based on their cell surface expression of the glycoprotein Ly6C. Ly6C …

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Contact Us | GEM Plumbing & Heating

365 Pleasant St #100. Fall River, MA 02721. Phone: (508)796-8292. Questions? We''re Here To Help! Quality, Friendly Service in Southern New England. Chat With Us.

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The Complex Role of Regulatory T Cells in Immunity and Aging

2021-1-27 · 10.1084/jem.20191542 [PMC free article] [Google Scholar] 37. Almanan MA, Raynor J, Chougnet C, Salamonis N, Amarachintha S, Steinbrecher K, et al. Type 1 regulatory T cells (Tr1) homeostasis and function in …

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Upregulation of VCAM-1 and ICAM-1 at Atherosclerosis …

1998-5-1 · Reagents. The sources and working dilutions of both primary antibodies and irrelevant control immunoglobulins are listed in the Table ing a cell-surface ELISA, Hahne et 15 al showed that antibodies to VCAM-1 and ICAM-1 react with antigens expressed on the …

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Enhanced photoluminescence properties of a carbon dot ...

2018-5-15 · 1. Introduction. Recently, a new class of fluorescent carbon nanomaterials, so-called carbon dot systems (CDSs), have attracted great attention due to their excellent photoluminescence (PL) properties, and low-toxicity .Additional advantages are a high water-dispersibility and photostability, a strong chemical inertness as well as easy surface functionalization .

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Surface chemistry-mediated modulation of adsorbed …

2021-1-28 · @article{osti_1777295, title = {Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets}, author = {Vincent, Michael P. and Bobbala, Sharan and Karabin, Nicholas B. and Frey, Molly and Liu, Yugang and Navidzadeh, Justin O. and Stack, Trevor and Scott, Evan A.}, abstractNote = {Controlling nanocarrier interactions ...

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Plumbing, Drains, HVAC & Electrical Services in RI & MA

GEM Plumbing & Heating is here for you and your home. As COVID-19 affects our day-to-day, we''re providing contactless service to ensure your safety ing measures like physical distancing, verbal signatures, and cooperative steps to remove obstacles, we''ll respect your space and avoid unnecessary contact from start to …

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Enterocyte-specific A20 deficiency sensitizes to tumor ...

tibility to chemically induced colitis (Steinbrecher et al., 2008). An important step in the inflammatory process in these NF- B– deficient mice involves the sensitization of NF- B–deficient epithelial cells to TNF-induced apoptosis, compromising epi-thelial integrity and allowing bacterial translocation into the mu-

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Inhibition of T cell response to native low-density ...

2010-5-10 · Oxidation of LDL extinguishes its recognition by T cells. We further analyzed the relationship between oxidation and the antigenicity of LDL particles by exposing T cell hybridomas to LDL particles that were oxidized by copper for various times, resulting in a range of oxidation (Fig. 1, E–G).For all T cell hybridomas, there was an inverse relationship between the degree of oxidation and the ...

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Small intestinal eosinophils regulate Th17 cells by ...

The small intestinal lamina propria (LP) contains a variety of immune cells. These include Th17 cells, a subset of activated CD4 + T cells characterized by the production of IL-17A, IL-17F, IL-21, and IL-22 (Korn et al., 2009).Th17 cells have the potential to protect or damage the intestinal tissue environment, so their activity must be tightly regulated (O''Connor et al., 2009; Morrison et ...

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A copper based catalyst for poly-urethane synthesis from ...

Preparation of polyurethane foam To a neat glass vial, 0.5 g of bamboo polyol and 0.5 g of IPDI is added and the mixture is stirred well for 2 minutes. 0.1 g of the above prepared Cu-based catalyst is weighed and dispersed in 1 mL of water and mechanically mixed for 5 minutes …

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Imaging of the immune system – towards a subcellular and ...

2020-3-5 · The complexity of the immune system makes the imaging of various immune cells as a whole demanding but also worthwhile. Although non-optical methods, such as positron emission tomography (PET) and magnetic resonance imaging (MRI) exist (Willmann et al., …

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Carbon dots with concentration-modulated fluorescence ...

2020-8-1 · The morphology of the CDs and ZrCDs was measured by transmission electron microscopy (TEM) performed on a JEOL JEM-1011 electron microscope operating at an acceleration voltage of 100 kV. Absolute fluorescence quantum yield was calculated by an absolute quantum efficiency tester (Japan Waterfront C …

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